Items of some interest:

These are my recent Pin​board​.in links:

  • [1203.1644] The B36/​S125 “2×2″ Life-​​Like Cel­lu­lar Automaton

    “The B36/​S125 (or “2x2”) cel­lu­lar automa­ton is one that takes place on a 2D square lat­tice much like Conway’s Game of Life. Although it exhibits high-​​level behav­iour that is sim­i­lar to Life, such as chaotic but even­tu­ally sta­ble evo­lu­tion and the exis­tence of a nat­ural diag­o­nal glider, the indi­vid­ual objects that the rule con­tains gen­er­ally look very dif­fer­ent from their Life coun­ter­parts. In this arti­cle, a his­tory of notable dis­cov­er­ies in the 2×2 rule is pro­vided, and the fun­da­men­tal pat­terns of the automa­ton are described. Some the­o­ret­i­cal results are derived along the way, includ­ing a proof that the speed lim­its for diag­o­nal and orthog­o­nal space­ships in this rule are c/​3 and c/​2, respec­tively. A Mar­go­lus block cel­lu­lar automa­ton that 2×2 emu­lates is inves­ti­gated, and in par­tic­u­lar a fam­ily of oscil­la­tors made up entirely of 2 x 2 blocks are ana­lyzed and used to show that there exist oscil­la­tors with period 2m(2k — 1) for any inte­gers m,k geq 1.”

    cellular-​​automata artificial-​​life discrete-​​mathematics emer­gence mathematical-​​recreations nudge-​​targets
  • [1203.1034] Gen­eral Com­plex Poly­no­mial Root Solver and Its Fur­ther Opti­miza­tion for Binary Microlenses

    “We present a new algo­rithm to solve poly­no­mial equa­tions, and pub­lish its code, which is 1.6−3 times faster than the ZROOTS sub­rou­tine that is com­mer­cially avail­able from Numer­i­cal Recipes, depend­ing on appli­ca­tion. The largest improve­ment, when com­pared to naive solvers, comes from a fail-​​safe pro­ce­dure that per­mits us to skip the major­ity of the cal­cu­la­tions in the great major­ity of cases, with­out risk­ing cat­a­strophic fail­ure in the few cases that these are actu­ally required. Sec­ond, we iden­tify a dis­crim­i­nant that enables a ratio­nal choice between Laguerre’s Method and Newton’s Method (or a new inter­me­di­ate method) on a case-​​by-​​case basis. We briefly review the his­tory of root solv­ing and demon­strate that “Newton’s Method” was dis­cov­ered nei­ther by New­ton (1671) nor by Raph­son (1690), but only by Simp­son (1740). Some of the argu­ments lead­ing to this con­clu­sion were first given by the British his­to­rian of sci­ence Nick Koller­strom in 1992, but these do not appear to have pen­e­trated the astro­nom­i­cal com­mu­nity. Finally, we argue that Numer­i­cal Recipes should vol­un­tar­ily sur­ren­der its copy­right pro­tec­tion for non-​​profit appli­ca­tions, despite the fact that, in this par­tic­u­lar case, such pro­tec­tion was the major stim­u­lant for devel­op­ing our improved algorithm.”

    algo­rithms numerical-​​methods optics nudge-​​targets
  • [1203.1065] Sub­space clus­ter­ing of high-​​dimensional data: a pre­dic­tive approach

    “In sev­eral appli­ca­tion domains, high-​​dimensional obser­va­tions are col­lected and then analysed in search for nat­u­rally occur­ring data clus­ters which might pro­vide fur­ther insights about the nature of the prob­lem. In this paper we describe a new approach for par­ti­tion­ing such high-​​dimensional data. Our assump­tion is that, within each clus­ter, the data can be approx­i­mated well by a lin­ear sub­space esti­mated by means of a prin­ci­pal com­po­nent analy­sis (PCA). The pro­posed algo­rithm, Pre­dic­tive Sub­space Clus­ter­ing (PSC) par­ti­tions the data into clus­ters while simul­ta­ne­ously esti­mat­ing cluster-​​wise PCA para­me­ters. The algo­rithm min­imises an objec­tive func­tion that depends upon a new mea­sure of influ­ence for PCA mod­els. A penalised ver­sion of the algo­rithm is also described for car­ry­ing our simul­ta­ne­ous sub­space clus­ter­ing and vari­able selec­tion. The con­ver­gence of PSC is dis­cussed in detail, and exten­sive sim­u­la­tion results and com­par­isons to com­pet­ing meth­ods are pre­sented. The com­par­a­tive per­for­mance of PSC has been assessed on six real gene expres­sion data sets for which PSC often pro­vides state-​​of-​​art results.”

    ain’t-performance-space sta­tis­tics clus­ter­ing cure-​​for-​​dimensionality algo­rithms
  • [1203.1067] Cor­ti­cal free asso­ci­a­tion dynam­ics: dis­tinct phases of a latch­ing network

    “… The occur­rence and dura­tion of latch­ing dynam­ics is found through sim­u­la­tions to depend crit­i­cally on the strength of local attrac­tor states, expressed in the Potts model by a para­me­ter w. Here we describe with sim­u­la­tions and then ana­lyt­i­cally the bound­aries between dis­tinct phases of no latch­ing, of tran­sient and sus­tained latch­ing, deriv­ing a phase dia­gram in the plane w-​​T, where T param­e­trizes ther­mal noise effects. Impli­ca­tions for real cor­ti­cal dynam­ics are briefly reviewed in the conclusions.”

    neural-​​networks biologically-​​inspired dynamical-​​systems emergent-​​design nudge-​​targets
  • Fright­en­ingly Ambi­tious Startup Ideas

    “One of the more sur­pris­ing things I’ve noticed while work­ing on Y Com­bi­na­tor is how fright­en­ing the most ambi­tious startup ideas are. In this essay I’m going to demon­strate this phe­nom­e­non by describ­ing some. Any one of them could make you a bil­lion­aire. That might sound like an attrac­tive prospect, and yet when I describe these ideas you may notice you find your­self shrink­ing away from them.”

    every-​​idea-​​is-​​born star­tups inno­va­tion
  • [1201.6054] Attain­abil­ity in Repeated Games with Vec­tor Payoffs

    “We intro­duce the con­cept of attain­able sets of pay­offs in two-​​player repeated games with vec­tor pay­offs. A set of pay­off vec­tors is called {em attain­able} if player 1 can ensure that there is a finite hori­zon $T$ such that after time $T$ the dis­tance between the set and the cumu­la­tive pay­off is arbi­trar­ily small, regard­less of what strat­egy player 2 is using. This paper focuses on the case where the attain­able set con­sists of one pay­off vec­tor. In this case the vec­tor is called an attain­able vec­tor. We study prop­er­ties of the set of attain­able vec­tors, and char­ac­ter­ize when a spe­cific vec­tor is attain­able and when every vec­tor is attainable.”

    game-​​theory agent-​​based multiobjective-​​optimization nudge-​​targets
  • [1203.1080] Data Struc­ture Lower Bounds on Ran­dom Access to Grammar-​​Compressed Strings

    “In this paper we inves­ti­gate the prob­lem of build­ing a sta­tic data struc­ture that rep­re­sents a string s using space close to its com­pressed size, and allows fast access to indi­vid­ual char­ac­ters of s. …”

    gram­mars algo­rithms nudge-​​targets

Items of some interest…

These are my recent Pin​board​.in links:

  • [1105.4335] Phys­i­cal approaches to the dynam­ics of genetic cir­cuits: A tutorial

    “Cel­lu­lar behav­ior is gov­erned by gene reg­u­la­tory processes that are intrin­si­cally dynamic and non­lin­ear, and are sub­ject to non-​​negligible amounts of ran­dom fluc­tu­a­tions. Such con­di­tions are ubiq­ui­tous in phys­i­cal sys­tems, where they have been stud­ied for decades using the tools of sta­tis­ti­cal and non­lin­ear physics. The goal of this review is to show how approaches tra­di­tion­ally used in physics can help in reach­ing a systems-​​level under­stand­ing of liv­ing cells. To that end, we present an overview of the dynam­i­cal phe­nom­ena exhib­ited by genetic cir­cuits and their func­tional sig­nif­i­cance. We also describe the the­o­ret­i­cal and exper­i­men­tal approaches that are being used to unravel the rela­tion­ship between cir­cuit struc­ture and func­tion in dynam­i­cal cel­lu­lar processes under the influ­ence of noise, both at the single-​​cell level and in cel­lu­lar pop­u­la­tions, where inter­cel­lu­lar cou­pling plays an impor­tant role.”

    systems-​​biology biological-​​engineering genetic-​​regulatory-​​networks emergent-​​design bio­chem­istry overview
  • [1106.0371] A Novel Image Seg­men­ta­tion Enhance­ment Tech­nique based on Active Con­tour and Topo­log­i­cal Alignments

    “Topo­log­i­cal align­ments and snakes are used in image pro­cess­ing, par­tic­u­larly in locat­ing object bound­aries. Both of them have their own advan­tages and lim­i­ta­tions. To improve the over­all image bound­ary detec­tion sys­tem, we focused on devel­op­ing a novel algo­rithm for image pro­cess­ing. The algo­rithm we pro­pose to develop will based on the active con­tour method in con­junc­tion with topo­log­i­cal align­ments method to enhance the image detec­tion approach. The algo­rithm presents novel tech­nique to incor­po­rate the advan­tages of both Topo­log­i­cal Align­ments and snakes. Where the ini­tial seg­men­ta­tion by Topo­log­i­cal Align­ments is firstly trans­formed into the input of the snake model and begins its evolve­ment to the inter­ested object bound­ary. The results show that the algo­rithm can deal with low con­trast images and shape cells, demon­strate the seg­men­ta­tion accu­racy under weak image bound­aries, which respon­si­ble for lack­ing accu­racy in image detect­ing tech­niques. We have achieved bet­ter seg­men­ta­tion and bound­ary detect­ing for the image, also the abil­ity of the sys­tem to improve the low con­trast and deal with over and under segmentation.”

    image-​​segmentation algo­rithms nudge-​​targets
  • [1106.2508] A Prac­ti­cal Imple­men­ta­tion of the Bernoulli Factory

    “…While sev­eral prac­ti­cal uses of the method have been pro­posed in Monte Carlo appli­ca­tions, these require an imple­men­ta­tion frame­work that is flex­i­ble, gen­eral and effi­cient. We present such a frame­work for func­tions that are either strictly lin­ear, con­cave, or con­vex on the unit inter­val using a series of enve­lope func­tions defined through a cas­cade, and show that this method not only greatly reduces the num­ber of input bits needed in prac­tice com­pared to other cur­rently pro­posed solu­tions for more spe­cific prob­lems, but can eas­ily be cou­pled to more asymp­tot­i­cally effi­cient meth­ods to allow for the­o­ret­i­cally strong results.”

    algo­rithms numerical-​​methods Monte-​​Carlo-​​simulation probability-​​theory nudge-​​targets
  • [1105.1729] Evo­lu­tion­ary search for novel super­hard materials

    “We have devel­oped a method for pre­dic­tion of the hard­est crys­tal struc­tures in a given chem­i­cal sys­tem. It is based on the evo­lu­tion­ary algo­rithm USPEX and electronegativity-​​based hard­ness model that we have aug­mented with bond-​​valence model and graph the­ory. These exten­sions enable cor­rect descrip­tion of the hard­ness of lay­ered, mol­e­c­u­lar and low-​​symmetry crys­tal struc­tures. Apply­ing this method to C and TiO2, we have (i) obtained a num­ber of low-​​energy car­bon struc­tures with hard­ness slightly lower than dia­mond and (ii) proved that TiO2 in any of its pos­si­ble poly­morphs can­not be the hard­est oxide, its hard­ness being below 17 GPa.”

    materials-​​science genetic-​​algorithm condensed-​​matter sim­u­la­tion nudge-​​targets
  • [1109.0573] Phase Retrieval via Matrix Completion

    “This paper con­sid­ers the fun­da­men­tal prob­lem of recov­er­ing a gen­eral sig­nal, an image for exam­ple, from the mag­ni­tude of its Fourier trans­form. This prob­lem, also known as phase retrieval, arises in many appli­ca­tions and has chal­lenged engi­neers, physi­cists, and math­e­mati­cians for decades. Its ori­gin comes from the fact that detec­tors can often times only record the squared mod­u­lus of the Fres­nel or Fraun­hofer dif­frac­tion pat­tern of the radi­a­tion that is scat­tered from an object. In such set­tings, one can­not mea­sure the phase of the opti­cal wave reach­ing the detec­tor and, there­fore, much infor­ma­tion about the scat­tered object or the opti­cal field is lost since, as is well known, the phase encodes a lot of the struc­tural con­tent of the image we wish to form.”

    image-​​processing inverse-​​problems signal-​​processing system-​​identification frequency-​​space algo­rithms nudge-​​targets numerical-​​methods
  • [1109.0807] Har­monic Analy­sis of Boolean Net­works: Deter­mi­na­tive Power and Perturbations

    “Con­sider a large Boolean net­work with a feed for­ward struc­ture. Given a prob­a­bil­ity dis­tri­b­u­tion for the inputs, can one find-​​possibly small-​​collections of input nodes that deter­mine the states of most other nodes in the network?…”

    Boolean-​​networks Kauff­ma­nia com­plex­ol­ogy discrete-​​mathematics mathematical-​​recreations nudge-​​targets
  • [0801.0830] Evo­lu­tion of cen­tral pat­tern gen­er­a­tors for the con­trol of a five-​​link bipedal walk­ing mechanism

    “With the aim of pro­duc­ing a sta­ble human-​​like bipedal gait, a five-​​link pla­nar walk­ing mech­a­nism is cou­pled with a cen­tral pat­tern gen­er­a­tor (CPG) neural net­work, con­sist­ing of units based on Matsuoka’s half-​​center oscil­la­tor model with a firm basis in neu­ro­phys­i­ol­ogy. As a min­i­mal­is­tic approach to bipedal walk­ing, this type of walk­ing mech­a­nism con­tains only four actu­a­tors, and is lack­ing feet and ankles. The mech­a­nism is sim­u­lated with accu­rate physics, allow­ing real­is­tic fit­ness eval­u­a­tions for the cre­ation of CPG con­trollers through evo­lu­tion­ary com­pu­ta­tion. The oscil­la­tory para­me­ters, inter­nal con­nec­tiv­ity struc­ture, and exter­nal feed­back path­ways of the net­works are deter­mined through genetic algo­rithms (GA) opti­miza­tion. The evolved CPG net­works are trans­ferred to a hard­ware imple­men­ta­tion of the mech­a­nism, to test their per­for­mance under real-​​world dynam­ics. Results con­firm that the bio­log­i­cally inspired CPG model is very well suited for con­trol­ling legged loco­mo­tion, since a diverse man­i­fes­ta­tion of CPG net­works (with and with­out exter­nal feed­back) have been observed to suc­ceed dur­ing the course of GA eval­u­a­tions. Obser­va­tions also imply that while the CPG mech­a­nism is inher­ently able to sus­tain a sta­ble gait, the uti­liza­tion of feed­back path­ways makes the gait more human-​​like and is needed to pro­vide a means to adapt to irreg­u­lar­i­ties in the environment.”

    robot­ics engineering-​​design genetic-​​algorithm neural-​​networks cyber­net­ics nudge-​​targets
  • [1109.3351] Phys­i­cal lim­its on coop­er­a­tive protein-​​DNA bind­ing and the kinet­ics of com­bi­na­to­r­ial tran­scrip­tion regulation

    “Much of the com­plex­ity observed in gene reg­u­la­tion orig­i­nates from coop­er­a­tive protein-​​DNA bind­ing. While stud­ies of the tar­get search of pro­teins for their spe­cific bind­ing sites on the DNA have revealed design prin­ci­ples for the quan­ti­ta­tive char­ac­ter­is­tics of protein-​​DNA inter­ac­tions, no such prin­ci­ples are known for the coop­er­a­tive inter­ac­tions between DNA-​​binding pro­teins. We con­sider a sim­ple the­o­ret­i­cal model for two inter­act­ing tran­scrip­tion fac­tor (TF) species, search­ing for and bind­ing to two adja­cent tar­get sites hid­den in the genomic back­ground. We study the kinetic com­pe­ti­tion of a dimer search path­way and a monomer search path­way, as well as the steady-​​state reg­u­la­tion func­tion medi­ated by the two TFs over a broad range of TF-​​TF inter­ac­tion strengths. Using a tran­scrip­tional AND-​​logic as exem­plary func­tional con­text, we iden­tify the func­tion­ally desir­able regime for the inter­ac­tion. We find that both weak and very strong TF-​​TF inter­ac­tions are favor­able, albeit with dif­fer­ent char­ac­ter­is­tics. How­ever, there is also an unfa­vor­able regime of inter­me­di­ate inter­ac­tions where the genetic response is pro­hib­i­tively slow.”

    biological-​​engineering genetic-​​regularory-​​networks systems-​​biology emergent-​​design nudge-​​targets
  • [1109.6874] #h00t: Cen­sor­ship Resis­tant Microblogging

    “Microblog­ging ser­vices such as Twit­ter are an increas­ingly impor­tant way to com­mu­ni­cate, both for indi­vid­u­als and for groups through the use of hash­tags that denote top­ics of con­ver­sa­tion. How­ever, groups can be eas­ily blocked from com­mu­ni­cat­ing through block­ing of posts with the given hash­tags. We pro­pose #h00t, a sys­tem for cen­sor­ship resis­tant microblog­ging. #h00t presents an inter­face that is much like Twit­ter, except that hash­tags are replaced with very short hashes (e.g., 24 bits) of the group iden­ti­fier. Nat­u­rally, with such short hashes, hash­tags from dif­fer­ent groups may col­lide and #h00t users will actu­ally seek to cre­ate col­li­sions. By encrypt­ing all posts with keys derived from the group iden­ti­fiers, #h00t client soft­ware can fil­ter out other groups’ posts while mak­ing such fil­ter­ing dif­fi­cult for the adver­sary. In essence, by lever­ag­ing col­li­sions, groups can tun­nel their posts in other groups’ posts. A cen­sor could not block a given group with­out also block­ing the other groups with col­lid­ing hash­tags. We eval­u­ate the fea­si­bil­ity of #h00t through traces col­lected from Twit­ter, show­ing that a sin­gle mod­ern com­puter has enough com­pu­ta­tional through­put to encrypt every tweet sent through Twit­ter in real time. We also use these traces to ana­lyze the band­width and anonymity trade­offs that would come with dif­fer­ent vari­a­tions on how group iden­ti­fiers are encoded and hash­tags are selected to pur­pose­fully col­lide with one another.”

    social-​​media steganog­ra­phy robust­ness activism cute
  • [1107.0414] A ran­dom walk on image patches

    “In this paper we address the prob­lem of under­stand­ing the suc­cess of algo­rithms that orga­nize patches accord­ing to graph-​​based met­rics. Algo­rithms that ana­lyze patches extracted from images or time series have led to state-​​of-​​the art tech­niques for clas­si­fi­ca­tion, denois­ing, and the study of non­lin­ear dynam­ics. The main con­tri­bu­tion of this work is to pro­vide a the­o­ret­i­cal expla­na­tion for the above exper­i­men­tal obser­va­tions. Our approach relies on a detailed analy­sis of the com­mute time met­ric on pro­to­typ­i­cal graph mod­els that epit­o­mize the geom­e­try observed in gen­eral patch graphs.…”

    image-​​segmentation image-​​analysis algo­rithms com­bi­na­torics nudge-​​targets
  • [1107.0385] An algo­rithm for autonomously plot­ting solu­tion sets in the pres­ence of turn­ing points

    “Plot­ting solu­tion sets for par­tic­u­lar equa­tions may be com­pli­cated by the exis­tence of turn­ing points. Here we describe an algo­rithm which not only over­comes such prob­lem­atic points, but does so in the most gen­eral of set­tings. Appli­ca­tions of the algo­rithm are high­lighted through two exam­ples: the first pro­vides ver­i­fi­ca­tion, while the sec­ond demon­strates a non-​​trivial appli­ca­tion. The lat­ter is fol­lowed by a thor­ough run-​​time analy­sis. While both exam­ples deal with bivari­ate equa­tions, it is dis­cussed how the algo­rithm may be gen­er­al­ized for space curves in $R^{3}$.”

    visu­al­iza­tion math­e­mat­ics graph­ics approx­i­ma­tion algo­rithms nudge-​​targets
  • [1105.1033] Adap­tively Learn­ing the Crowd Kernel

    “We intro­duce an algo­rithm that, given n objects, learns a sim­i­lar­ity matrix over all n^2 pairs, from crowd­sourced data alone. The algo­rithm sam­ples responses to adap­tively cho­sen triplet-​​based relative-​​similarity queries. Each query has the form “is object ‘a’ more sim­i­lar to ‘b’ or to ‘c’?” and is cho­sen to be max­i­mally infor­ma­tive given the pre­ced­ing responses. The out­put is an embed­ding of the objects into Euclid­ean space (like MDS); we refer to this as the “crowd ker­nel.” SVMs reveal that the crowd ker­nel cap­tures promi­nent and sub­tle fea­tures across a num­ber of domains, such as “is striped” among neck­ties and “vowel vs. con­so­nant” among letters.”

    clas­si­fi­ca­tion ontology-​​discovery crowd­sourc­ing feature-​​extraction algo­rithms nudge-​​targets performance-​​space-​​analysis
  • [1109.1030] An Algo­rithm for Detect­ing Intrin­si­cally Knot­ted Graphs

    “We describe an algo­rithm that rec­og­nizes some (per­haps all) intrin­si­cally knot­ted (IK) graphs, and can help find knot­less embed­dings for graphs that are not IK. The algo­rithm, imple­mented as a Math­e­mat­ica pro­gram, has already been used by Gold­berg, Mattman, and Naimi [6] to greatly expand the list of known minor min­i­mal IK graphs, and to find knot­less embed­dings for some graphs that had pre­vi­ously resisted attempts to clas­sify them as IK or non-​​IK.”

    com­bi­na­torics topol­ogy algo­rithms nudge-​​targets
  • [1109.5635] Approx­i­mat­ing Edit Dis­tance in Near-​​Linear Time

    “We show how to com­pute the edit dis­tance between two strings of length n up to a fac­tor of 2^{~O(sqrt(log n))} in n^(1+o(1)) time. This is the first sub-​​polynomial approx­i­ma­tion algo­rithm for this prob­lem that runs in near-​​linear time, improv­ing on the state-​​of-​​the-​​art n^(1/3+o(1)) approx­i­ma­tion. Pre­vi­ously, approx­i­ma­tion of 2^{~O(sqrt(log n))} was known only for embed­ding edit dis­tance into l_​1, and it is not known if that embed­ding can be com­puted in less than qua­dratic time.”

    algo­rithms string-​​editing Levenshtein-​​distance rewriting-​​systems bioin­for­mat­ics nudge-​​targets
  • [1107.1866] Priority-​​based task reas­sign­ments in hier­ar­chi­cal 2D mesh-​​connected sys­tems using tableaux

    “Task reas­sign­ments in 2D mesh-​​connected sys­tems (2D-​​MSs) have been researched and sim­u­lated for sev­eral decades. We pro­pose a hier­ar­chi­cal 2D mesh-​​connected sys­tem (2D-​​HMS) in order to exploit the reg­u­lar nature of a 2D-​​MS. In our approach priority-​​based task assign­ments and reas­sign­ments in a 2D-​​HMS are rep­re­sented by tableaux and their algo­rithms. We pro­vide exam­ples of priority-​​based task reas­sign­ments in a 2D-​​HMS in which task relo­ca­tions are sim­ply reduced to a jeu de taquin slide.”

    sched­ul­ing operations-​​research algo­rithms grid-​​computing opti­miza­tion nudge-​​targets
  • [1101.4744] Clus­ter­ing func­tional data using wavelets

    “We present two meth­ods for detect­ing pat­terns and clus­ters in high dimen­sional time-​​dependent func­tional data. Our meth­ods are based on wavelet-​​based sim­i­lar­ity mea­sures, since wavelets are well suited for iden­ti­fy­ing highly dis­crim­i­nant local time and scale fea­tures. The mul­tires­o­lu­tion aspect of the wavelet trans­form pro­vides a time-​​scale decom­po­si­tion of the sig­nals allow­ing to visu­al­ize and to clus­ter the func­tional data into homo­ge­neous groups. For each input func­tion, through its empir­i­cal orthog­o­nal wavelet trans­form the first method uses the dis­tri­b­u­tion of energy across scales gen­er­ate a handy num­ber of fea­tures that can be suf­fi­cient to still make the sig­nals well dis­tin­guish­able. Our new sim­i­lar­ity mea­sure com­bined with an effi­cient fea­ture selec­tion tech­nique in the wavelet domain is then used within more or less clas­si­cal clus­ter­ing algo­rithms to effec­tively dif­fer­en­ti­ate among high dimen­sional pop­u­la­tions. The sec­ond method uses dis­sim­i­lar­ity mea­sures between the whole time-​​scale rep­re­sen­ta­tions and are based on wavelet-​​coherence tools. The clus­ter­ing is then per­formed using a k-​​centroid algo­rithm start­ing from these dis­sim­i­lar­i­ties. Prac­ti­cal per­for­mance of these meth­ods that jointly designs both the fea­ture selec­tion in the wavelet domain and the clas­si­fi­ca­tion dis­tance is demon­strated through sim­u­la­tions as well as daily pro­files of the French elec­tric­ity power demand.”

    clas­si­fi­ca­tion time-​​series feature-​​extraction machine-​​learning multiobjective-​​optimization ontology-​​discovery wavelets nudge-​​targets
  • [1105.3726] Con­trol­ling Com­plex Net­works with Com­pen­satory Perturbations

    “The response of com­plex net­works to per­tur­ba­tions is of utmost impor­tance in areas as diverse as ecosys­tem man­age­ment, emer­gency response, and cell repro­gram­ming. A fun­da­men­tal prop­erty of net­works is that the per­tur­ba­tion of one node can affect other nodes, in a process that may cause the entire or sub­stan­tial part of the sys­tem to change behav­ior and pos­si­bly col­lapse. Recent research in meta­bolic and food-​​web net­works has demon­strated the con­cept that net­work dam­age caused by exter­nal per­tur­ba­tions can often be mit­i­gated or reversed by the appli­ca­tion of com­pen­satory per­tur­ba­tions. Com­pen­satory per­tur­ba­tions are con­strained to be phys­i­cally admis­si­ble and amenable to imple­men­ta­tion on the net­work. How­ever, the sys­tem­atic iden­ti­fi­ca­tion of com­pen­satory per­tur­ba­tions that con­form to these con­straints remains an open prob­lem. Here, we present a method to con­struct com­pen­satory per­tur­ba­tions that can con­trol the fate of gen­eral net­works under such con­straints. Our approach accounts for the full non­lin­ear behav­ior of real com­plex net­works and can bring the sys­tem to a desir­able tar­get state even when this state is not directly acces­si­ble. Appli­ca­tions to genetic net­works show that com­pen­satory per­tur­ba­tions are effec­tive even when lim­ited to a small frac­tion of all nodes in the net­work and that they are far more effec­tive when lim­ited to the highest-​​degree nodes. The approach is con­cep­tu­ally sim­ple and com­pu­ta­tion­ally effi­cient, mak­ing it suit­able for the res­cue, con­trol, and repro­gram­ming of large com­plex net­works in var­i­ous domains.”

    emergent-​​design com­plex­ol­ogy con­trol biological-​​engineering nudge-​​targets
  • [1109.1275] A For­mal Ver­i­fi­ca­tion Approach to the Design of Syn­thetic Gene Networks

    “The design of genetic net­works with spe­cific func­tions is one of the major goals of syn­thetic biol­ogy. How­ever, con­struct­ing bio­log­i­cal devices that work “as required” remains chal­leng­ing, while the cost of uncov­er­ing flawed designs exper­i­men­tally is large. To address this issue, we pro­pose a fully auto­mated frame­work that allows the cor­rect­ness of syn­thetic gene net­works to be for­mally ver­i­fied in sil­ico from rich, high level func­tional spec­i­fi­ca­tions. Given a device, we auto­mat­i­cally con­struct a math­e­mat­i­cal model from exper­i­men­tal data char­ac­ter­iz­ing the parts it is com­posed of. The spe­cific model struc­ture guar­an­tees that all exper­i­men­tal obser­va­tions are cap­tured and allows us to con­struct finite abstrac­tions through poly­he­dral oper­a­tions. The cor­rect­ness of the model with respect to tem­po­ral logic spec­i­fi­ca­tions can then be ver­i­fied auto­mat­i­cally using meth­ods inspired by model check­ing. Over­all, our pro­ce­dure is con­ser­v­a­tive but it can fil­ter through a large num­ber of poten­tial device designs and select few that sat­isfy the spec­i­fi­ca­tion to be imple­mented and tested fur­ther exper­i­men­tally. Illus­tra­tive exam­ples of the appli­ca­tion of our meth­ods to the design of sim­ple syn­thetic gene net­works are included.”

    genetic-​​regulatory-​​networks bioin­for­mat­ics biological-​​engineering design-​​automation emergent-​​design acceptance-​​testing performance-​​measure nudge
  • [1108.1150] Epis­ta­sis can lead to frag­mented neu­tral spaces and con­tin­gency in evolution

    “Under neu­tral rec­i­p­ro­cal sign epis­ta­sis, two genetic changes are jointly neu­tral, even though their indi­vid­ual effects are dele­te­ri­ous. By using the widely stud­ied map­ping from an RNA sequence to sec­ondary struc­ture, we inves­ti­gate the effect of this kind of epis­ta­sis on neu­tral spaces cor­re­spond­ing to net­works of geno­types that fold to the same sec­ondary struc­ture. Neu­tral net­works for RNA struc­tures with n bonds are typ­i­cally frag­mented into at least 2n dif­fer­ent neu­tral com­po­nents that can­not be con­nected by sin­gle point muta­tions. By exhaus­tive enu­mer­a­tion of all RNA sec­ondary struc­tures of sequences of length 15 we show that most net­works are not dom­i­nated by one neu­tral com­po­nent, but are rather bro­ken up into mul­ti­ple large com­po­nents. Although they gen­er­ate the same phe­no­type, com­po­nents of a sin­gle neu­tral net­work are het­ero­ge­neous, show­ing wide vari­a­tions in their robust­ness and their evolv­abil­ity. Both prop­er­ties are cor­re­lated with com­po­nent size, rather than with the size of their under­ly­ing neu­tral net­work. In par­tic­u­lar, sets of acces­si­ble phe­no­types can vary quite strongly between com­po­nents. Thus, the poten­tial for future inno­va­tion is con­tin­gent on which neu­tral com­po­nent a pop­u­la­tion occu­pies. We fur­ther argue that neu­tral rec­i­p­ro­cal sign epis­ta­sis may have sim­i­lar con­se­quences for neu­tral evo­lu­tion of other bio­log­i­cal sys­tems as well.”

    com­bi­na­torics RNA neutral-​​networks com­plex­ol­ogy bioin­for­mat­ics polymer-​​models mathematical-​​recreations nudge-​​targets
  • Old​Fonts​.com | About Us

    “Will­son founded 3IP in 1989 to self-​​publish a book of pre­ten­tious nature essays. Soon after, he found him­self tin­ker­ing with type design, and 3IP has since become known for its library of authentic-​​looking hand­writ­ing fonts—many of them mod­eled after his­tor­i­cal penmanship—and antique text simulations.”

    typog­ra­phy fonts hand­writ­ing
  • Col­lec­tive Wis­dom — Crooked Timber

    “More broadly, a sim­ple dic­tum such as ‘lis­ten to the experts’ isn’t going to work, pre­cisely because our most pow­er­ful meth­ods of gen­er­at­ing new knowl­edge (viz. the sci­ences) are not so much based on lis­ten­ing to indi­vid­ual experts, as on includ­ing these experts (and many oth­ers) in broader social sys­tems which expose them con­tin­u­ally to the ideas of oth­ers and vice-​​versa. Design­ing (or – per­haps bet­ter– nur­tur­ing) such sys­tems is hard to think about and hard to do – but it has to be the way forward.”

    via:arsyed wisdom-​​of-​​crowds com­plex­ol­ogy inno­va­tion cultural-​​assumptions cre­den­tial­ing problem-​​solving what-​​is-​​true-​​is-​​what-​​gets-​​said
  • [1109.1146] A Dis­trib­uted Mincut/​Maxflow Algo­rithm Com­bin­ing Path Aug­men­ta­tion and Push-​​Relabel

    “We develop a novel dis­trib­uted algo­rithm for the min­i­mum cut prob­lem. We pri­mar­ily aim at solv­ing large sparse prob­lems. Assum­ing ver­tices of the graph are par­ti­tioned into sev­eral regions, the algo­rithm per­forms path aug­men­ta­tions inside the regions and updates of the push-​​relabel style between the regions. The inter­ac­tion between regions is con­sid­ered expen­sive (regions are loaded into the mem­ory one-​​by-​​one or located on sep­a­rate machines in a net­work). The algo­rithm works in sweeps — passes over all regions. Let $B$ be the set of ver­tices inci­dent to inter-​​region edges of the graph. We present a sequen­tial and par­al­lel ver­sions of the algo­rithm which ter­mi­nate in at most $2|B|^2+1$ sweeps. The com­pet­ing algo­rithm by Delong and Boykov uses push-​​relabel updates inside regions. In the case of a fixed par­ti­tion we prove that this algo­rithm has a tight $O(n^2)$ bound on the num­ber of sweeps, where $n$ is the num­ber of ver­tices. We tested sequen­tial ver­sions of the algo­rithms on instances of maxflow prob­lems in com­puter vision. Exper­i­men­tally, the num­ber of sweeps required by the new algo­rithm is much lower than for the Delong and Boykov’s vari­ant. Large prob­lems (up to $108$ ver­tices and $6cdot 108$ edges) are solved using under 1GB of mem­ory in about 10 sweeps.”

    algo­rithms operations-​​research nudge-​​targets
  • [1105.4953] A fast near­est neigh­bor search algo­rithm based on vec­tor quantization

    “In this arti­cle, we pro­pose a new fast near­est neigh­bor search algo­rithm, based on vec­tor quan­ti­za­tion. Like many other branch and bound search algo­rithms [1,10], a pre­pro­cess­ing recur­sively par­ti­tions the data set into dis­jointed sub­sets until the num­ber of points in each part is small enough. In doing so, a search-​​tree data struc­ture is built. This pre­lim­i­nary recur­sive data-​​set par­ti­tion is based on the vec­tor quan­ti­za­tion of the empir­i­cal dis­tri­b­u­tion of the ini­tial data-​​set. Unlike pre­vi­ously cited meth­ods, this kind of par­ti­tions does not a pri­ori allow to elim­i­nate sev­eral brother nodes in the search tree with a sin­gle test. To over­come this dif­fi­culty, we pro­pose an algo­rithm to reduce the num­ber of tested brother nodes to a min­i­mal list that we call “friend Voronoi cells”. The com­plete descrip­tion of the method requires a deeper insight into the prop­er­ties of Delau­nay tri­an­gu­la­tions and Voronoi diagrams”

    algo­rithms search-​​algorithms data-​​analysis nudge-​​targets
  • [1108.0986] A prox­i­mal point algo­rithm for sequen­tial fea­ture extrac­tion applications

    “We pro­pose a prox­i­mal point algo­rithm to solve LAROS prob­lem, that is the prob­lem of find­ing a “large approx­i­mately rank-​​one sub­ma­trix”. This LAROS prob­lem is used to sequen­tially extract fea­tures in data. We also develop a new stop­ping cri­te­rion for the prox­i­mal point algo­rithm, which is based on the dual­ity con­di­tions of eps-​​optimal solu­tions of the LAROS prob­lem, with a the­o­ret­i­cal guar­an­tee. We test our algo­rithm with two image data­bases and show that we can use the LAROS prob­lem to extract appro­pri­ate com­mon fea­tures from these images.”

    algo­rithms image-​​segmentation feature-​​extraction nudge-​​targets
  • [1011.2348] Ergodic Con­trol and Poly­he­dral approaches to PageR­ank Optimization

    “We study a gen­eral class of PageR­ank opti­miza­tion prob­lems which con­sist in find­ing an opti­mal out­link strat­egy for a web site sub­ject to design con­straints. We con­sider both a con­tin­u­ous prob­lem, in which one can choose the inten­sity of a link, and a dis­crete one, in which in each page, there are oblig­a­tory links, fac­ul­ta­tive links and for­bid­den links. We show that the con­tin­u­ous prob­lem, as well as its dis­crete vari­ant when there are no con­straints cou­pling dif­fer­ent pages, can both be mod­eled by con­strained Markov deci­sion processes with ergodic reward, in which the web­mas­ter deter­mines the tran­si­tion prob­a­bil­i­ties of web­surfers. Although the num­ber of actions turns out to be expo­nen­tial, we show that an asso­ci­ated poly­tope of tran­si­tion mea­sures has a con­cise rep­re­sen­ta­tion, from which we deduce that the con­tin­u­ous prob­lem is solv­able in poly­no­mial time, and that the same is true for the dis­crete prob­lem when there are no cou­pling con­straints. We also pro­vide effi­cient algo­rithms, adapted to very large net­works. Then, we inves­ti­gate the qual­i­ta­tive fea­tures of opti­mal out­link strate­gies, and iden­tify in par­tic­u­lar assump­tions under which there exists a “mas­ter” page to which all con­trolled pages should point. We report numer­i­cal results on frag­ments of the real web graph.”

    opti­miza­tion PageR­ank operations-​​research algo­rithms nudge-​​targets

Items of some interest…

These are my recent Pin​board​.in links:

  • The Myth of the Sole Inven­tor by Mark Lem­ley :: SSRN

    “The the­ory of patent law is based on the idea that a lone genius can solve prob­lems that stump the experts, and that the lone genius will do so only if prop­erly incented. We deny patents on inven­tions that are “obvi­ous” to ordi­nar­ily inno­v­a­tive sci­en­tists in the field. Our goal is to encour­age extra­or­di­nary inven­tions – those that we wouldn’t expect to get with­out the incen­tive of a patent. The canon­i­cal story of the lone genius inven­tor is largely a myth. Edi­son didn’t invent the light bulb; he found a bam­boo fiber that worked bet­ter as a fil­a­ment in the light bulb devel­oped by Sawyer and Man, who in turn built on light­ing work done by oth­ers. Bell filed for his tele­phone patent on the very same day as an inde­pen­dent inven­tor, Elisha Gray; the case ulti­mately went to the U.S. Supreme Court, which filled an entire vol­ume of U.S. Reports resolv­ing the ques­tion of whether Bell could have a patent despite the fact that he hadn’t actu­ally got­ten the inven­tion to work at the time he filed. The Wright Broth­ers were the first to fly at Kitty Hawk, but their plane didn’t work very well, and was quickly sur­passed by air­craft built by Glenn Cur­tis and oth­ers – planes that the Wrights delayed by over a decade with patent law­suits. The point can be made more gen­eral: sur­veys of hun­dreds of sig­nif­i­cant new tech­nolo­gies show that almost all of them are invented simul­ta­ne­ously or nearly simul­ta­ne­ously by two or more teams work­ing inde­pen­dently of each other. Inven­tion appears in sig­nif­i­cant part to be a social, not an indi­vid­ual, phe­nom­e­non. Inven­tors build on the work of those who came before, and new ideas are often “in the air,” or result from changes in mar­ket demand or the avail­abil­ity of new or cheaper start­ing mate­ri­als. And in the few cir­cum­stances where that is not true – where inven­tions truly are “sin­gle­tons” – it is often because of an acci­dent or error in the exper­i­ment rather than a con­scious effort to invent. ”

    patents inno­va­tion intellectual-​​property lawyers

Items of some interest…

These are my recent Pin​board​.in links:

Items of some interest…

These are my recent Pin​board​.in links:

  • A sec­ond front

    “Increas­ingly, this seems to be a war for sur­vival.  I under­stand that tra­di­tional pub­lish­ers are get­ting more and more des­per­ate as the dig­i­tal rev­o­lu­tion pro­ceeds and they con­tinue to dither about how to address it.  But aca­d­e­mic fac­ulty mem­bers are the source of almost all the con­tent these pub­lish­ers pub­lish, so this behav­ior is an extreme exam­ple of bit­ing the hand that feeds them.  It is even more stu­pid, in my opin­ion, than the strat­egy of record­ing indus­try who is suing its own cus­tomers, because these pub­lish­ers are attack­ing a group that is both their cus­tomers and those who sup­ply them with a prod­uct in the first place.”

    copy­right academic-​​culture libraries good-​​eating-​​on-​​one-​​of-​​those disintermediation-​​targets
  • jQuery for Absolute Begin­ners: The Com­plete Series | Nettuts+

    “Hi every­one! Today, I posted the final screen­cast in my “jQuery for Absolute Begin­ners” series on the The­me­For­est Blog. If you’re unfa­mil­iar – over the course of about a month, I posted fif­teen video tuto­ri­als that teach you EXACTLY how to use the jQuery library. We start by down­load­ing the library and even­tu­ally work our way up to cre­at­ing an AJAX style-​​switcher. I’m very proud of this series; pos­si­bly more than any other that I’ve done for Envato.”

    javascript jQuery tuto­r­ial pod­cast video
  • Noodle­soft: Hazel FAQ

    “In gen­eral, Hazel can mon­i­tor any folder but keep in mind that cer­tain fold­ers may not be good can­di­dates. For instance, P2P and other apps that might down­load a file slowly, may have their files moved before they are com­pletely down­loaded. In cases like this, it is best if the pro­gram has an option to down­load to one folder then move them auto­mat­i­cally to another (Trans­mis­sion has such an option). This sec­ond folder is the one you should have Hazel mon­i­tor. Hazel does have spe­cial sup­port for Safari, Camino, Fire­fox, Mail and Speed Down­load and knows how to iden­tify when their down­loads are com­plete. We will be adding sup­port for more apps as time goes on so if you have a favorite app of yours you would like sup­ported, please let us know and we’ll look into adding support.”

    util­i­ties MacOS power-​​user sysad­min
  • Kate Oneal and the Myth­i­cal Ital­ian Restau­rant | xPro​gram​ming​.com

    ‘“The artist sug­gested this: ‘Let’s set a dead­line and total bud­get. I’ll keep you posted on how much is being spent, and of course we’ll have the pic­ture on the wall to look at. By the time we’re about half-​​way through, it should be of high enough qual­ity, and have enough pic­ture ele­ments, that we could stop any time. You’ll have more ideas, of course, but by then we’ll both have a sense of how fast we can progress, and you can choose the most valu­able things to add or change. You’ll have total con­trol over how the pic­ture winds up, and if you want to, we can stop on or before the money runs out.’ “Guido wasn’t entirely con­vinced. He wanted to know how he could be sure he wouldn’t be left with a hor­ri­bly ugly wall. The artist told him that she would guar­an­tee to paint it back over and stop any time he wanted, and said she would start by work­ing in some tem­po­rary pig­ment like chalk, so they could erase and change things easily.’

    project-​​management metaphor agile-​​management
  • Our Waste­ful Health Care Sys­tem — NYTimes​.com

    “The other key thing to pay atten­tion to is who this mar­ket­ing cam­paign was tar­geted at: key deci­sion­mak­ers at providers and insur­ance com­pa­nies. Those are the peo­ple who decide whether med­ical pro­ce­dures get ordered. It’s not patients. Patients aren’t going to expe­ri­ence a loss of free­dom or sat­is­fac­tion because an expert reviewer at the Inde­pen­dant Pay­ment Advi­sory Board makes the call as to whether a pro­ce­dure is med­ically ben­e­fi­cial, rather than the cor­re­spond­ing bureau­crat at their insur­ance provider or at the for-​​profit clinic they’re attending.”

    medical-​​culture cor­po­ratism public-​​policy insur­ance health­care mar­ket­ing
  • The Value of Fol­low­ing Pas­sion in a Job­less World — Lane Wal­lace — Life — The Atlantic

    “If I were a 22-​​year-​​old read­ing all this, the whole notion of adult­hood would seem like a prison sen­tence worth try­ing to avoid. But more impor­tantly, the entire premise upon which all this advice is based is false.  Pas­sion, despite how often we use the term to tout com­pany com­mit­ment or extol roman­tic excite­ment, is often mis­un­der­stood or con­fused with other motivations. Many peo­ple view dreams and pas­sion exactly as Brooks painted it: as a hope­lessly ide­al­is­tic, self­ish, or irre­spon­si­ble choice that is dia­met­ri­cally opposed to com­mit­ment to oth­ers, respon­si­bil­ity, secu­rity, or success. But I have spent the past year and a half research­ing a book about pas­sion and peo­ple who fol­low pas­sion­ate paths in life, and noth­ing I’ve found backs up that premise or belief. Indeed, I would argue that pas­sion is one of the most impor­tant ele­ments in any effort to improve a com­mu­nity, build some­thing of value in the world, and even sur­vive tough times or a daunt­ing econ­omy. The fact that it also tends to lead to a sense of ful­fill­ment within an indi­vid­ual is cer­tainly one of its benefits—but it’s not the dri­ving force that com­pels some­one down the pas­sion road.”

    work­life moti­va­tion David-Brooks-doesn’t-deserve-a-lot-of-respect pas­sion
  • Let It Roll — CFO Mag­a­zine — May 2011 Issue — CFO​.com

    “Sep­a­rat­ing the three deci­sions has enabled the com­pany to set tar­gets that are more ambi­tious, intel­li­gent, and moti­vat­ing, says Bogsnes. As a result, the fore­casts are less biased, and resource allo­ca­tion is more dynamic and self-​​regulating. “The ‘bank’ is open 12 months a year, not just six weeks in the fall,” he says. “By mak­ing resource deci­sions as late as pos­si­ble instead of in an annual bud­get, we have bet­ter infor­ma­tion — not just about project attrac­tive­ness but also about our capac­ity to fund or man new projects.“ Encour­aged by pos­i­tive results from aban­don­ing the bud­get, Sta­toil recently decided to abol­ish the cal­en­dar year as a plan­ning tool and intro­duce a busi­ness– and event-​​driven man­age­ment process in its stead.”

    bud­get­ing finance man­age­ment plan­ning fore­cast­ing agility
  • About That Recipe

    “Inter­preters are cou­plers. They enable the two peo­ple, groups, or cul­tures to under­stand each other because they under­stand both. While the meth­ods men­tioned above can facil­i­tate a fur­ther under­stand­ing of past food cul­tures, what about the other part of the connection—between peo­ple today and in the future? The his­tor­i­cal inter­preter has the unusual task of cou­pling peo­ple in one group about which she can only know a part, one group she knows well, and, if she pub­lishes her inter­pre­ta­tion in any form, one group in the future, about which she can­not know. The ques­tion is, then, not only what can we learn about mean­ings in the past, but how can we inter­pret those mean­ings to peo­ple today and in the future?”

    quotable his­tory
  • Lan­guage Log » Straw men and Bee Science

    “Let me start by say­ing that there’s a way to take all this that makes it entirely cor­rect. The key motive of sci­ence is expla­na­tion, and it’s often essen­tial to abstract away from the com­plex­i­ties of raw obser­va­tion, and so on. I took courses from Chom­sky as an under­grad­u­ate and a grad­u­ate stu­dent, and I’m grate­ful for what I learned from him, and for the emi­nently fair way that he always treated me. But increas­ingly, it seems to me, he has been ele­vat­ing his per­sonal dis­taste for the com­plex­i­ties of the real world into a sys­tem­atic phi­los­o­phy. To the extent that oth­ers accept these views, it excludes them from par­tic­i­pa­tion in (what I think are) the most promis­ing and excit­ing cur­rent direc­tions in the sci­ences of speech and language.”

    Noam-​​Chomsky theory-​​and-​​practice-​​sitting-​​in-​​a-​​tree bias sci­ence learning-​​from-​​data
  • Bozo Sapi­ens: Robert Owen: Laboriousness

    “Owen had neglected to notice that expec­ta­tions also change through cir­cum­stance. As our com­mu­nal con­di­tions advance, we all tend to want to become the prophet, not merely the con­gre­ga­tion. Once the prob­lem of sur­vival is solved, it’s no longer enough not to be starv­ing or abused or over­worked – we want per­sonal sat­is­fac­tion and self-​​direction. So, yes: some of the great names in busi­ness – the Low­ell mills, Hershey’s, Cadbury’s, Lever Broth­ers, Google – applied dilute Owenism to great effect, but suc­cess makes employ­ees become more indi­vid­u­al­ist and ask for more of their reward in cash, while hard times make share­hold­ers less gen­er­ous, point­ing out that plenty of peo­ple would take the job with­out the crêche, lec­ture series, or com­pany brass band. Shift­ing expec­ta­tion dri­ves the carousel for another turn; we remain ambiva­lent about work, this thing we do through most of our wak­ing lives, because we still don’t know what it is for.”

    institutional-​​design col­lab­o­ra­tion workantile-​​exchange diver­sity plan-​​for-​​change
  • Cal­cu­lated Risk: The Excess Vacant Hous­ing Supply

    “It is no sur­prise that Florida has the largest num­ber of excess vacant units and that Nevada has the largest per­cent­age of excess vacant units. What might be a sur­prise to some is that Cal­i­for­nia is below the U.S. average.”

    financial-​​crisis real-​​estate housing-​​bubble public-​​policy
  • Strin­gent Response: Sys­tems biol­ogy approach to strin­gent response

    “All this results in bac­te­ria gam­bling all the time: some react to stim­u­lus, some don’t, some pro­duce more pro­teins in response to it, some less. This leads to so called phe­no­typic het­ero­gene­ity, when oth­er­wise (genet­i­cally) iden­ti­cal bac­te­ria become very dif­fer­ent in terms of their responses. This could be a good thing and also could be a bad thing. Hav­ing a col­lec­tion of dif­fer­ent bugs instead of a clone army will pro­vide cer­tain ver­sa­til­ity: some are ready for one con­di­tions, and some are ready for oth­ers. For instance, some are ready to grow and divide right away and some are slower and more cau­tious. Both types of cells can be ben­e­fi­cial in dif­fer­ent con­di­tions: the active ones will drive the pop­u­la­tion growth, but will be sen­si­tive to the antibi­otic treat­ment, and the pas­sive ones will wait until the treat­ment is over and then they will come to life. Sounds like a good strat­egy (and it has a name, this strat­egy — “bed hedg­ing”) and I guess it is exactly the rea­son why clone armies never caught on.”

    diver­sity systems-​​biology evolutionary-​​biology game-​​theory emergent-​​design
  • Time as a Com­pet­i­tive Advan­tage | Mike Cohn’s Blog — Suc­ceed­ing With Agile®

    “Inno­va­tion has become a fer­tile area in which com­pa­nies seek com­pet­i­tive advan­tage today. This has served Apple well over the past decade. I don’t think inno­v­a­tive­ness will be going away soon as a source of com­pet­i­tive advan­tage. But I do won­der whether time is run­ning out on time as a com­pet­i­tive advan­tage. If agile and other inno­va­tions lead us to a world where all com­pa­nies can deliver new prod­ucts and ser­vices equally quickly, com­pa­nies will need to find newer ways to dif­fer­en­ti­ate themselves.”

    inno­va­tion com­pet­i­tive­ness agility strat­egy
  • See­ing Things On Mars: A Long His­tory of Mar­t­ian Illu­sions and Human Delu­sions |Parei­do­lia & Opti­cal Illu­sions | Space​.com

    “Humans have been see­ing strange things on the sur­face of Mars for cen­turies. From the 1700s up through the present day, wide­spread fame has been avail­able to any­one able to pro­duce even the slight­est bit of flimsy evi­dence that there’s Mar­t­ian life.”

    nanohis­tory Mars psy­choce­ram­ics astron­omy belief optical-​​illusions
  • The rise of Glen­core, the biggest com­pany you’ve never heard of | Busi­ness | The Guardian

    “But so jeal­ously has Glasen­berg guarded his pri­vacy that his name means noth­ing to the man on the street. For years he has avoided speeches and, until recently, had given only one inter­view – to his old uni­ver­sity mag­a­zine. If you live out­side the world of com­modi­ties trad­ing or cor­po­rate finance, Ivan Glasen­berg is prob­a­bly the Most Impor­tant Busi­ness­man You Have Never Heard Of.”

    glob­al­iza­tion finance cor­po­ra­tions pri­vacy transparency-it-ain’t
  • Datameer snags $9.25M more to ana­lyze mas­sive amounts of data | VentureBeat

    “Datameer, a com­pany that allows users to ana­lyze mas­sive amounts of data with­out tech­ni­cal know-​​how, today announced a sec­ond round of fund­ing for $9.25 mil­lion. The money will be used to hire addi­tional employ­ees for its engi­neer­ing, sales, and mar­ket­ing teams.”

    data-​​analysis data-​​mining star­tups fund­ing bub­b­li­cious
  • Plan Would Force U. of Wis­con­sin to Return $39-​​Million in U.S. Broad­band Grants — Wired Cam­pus — The Chron­i­cle of Higher Education

    “Another pro­vi­sion in the plan would bar any Uni­ver­sity of Wis­con­sin cam­pus from par­tic­i­pat­ing in advanced net­works con­nect­ing research insti­tu­tions world­wide, accord­ing to Mr. Evers’s memo. For exam­ple, the Madi­son cam­pus would have to with­draw from Internet2, a high-​​speed net­work­ing con­sor­tium, said Mr. Giroux.”

    pol­i­tics Wis­con­sin stu­pid­ity broad­band telecom­mu­ni­ca­tions cor­po­ratism